The 29-year-old striker bagged a brace, as the Red Devils maintained their seven-point lead over City, at the top of the League.
Van Persie, who moved from Arsenal in the summer, says he is surrounded by champions in a special team.
“This is a special team,” he told MUTV. “Everybody wants to help each other. Everybody’s keen for everyone to score. Defenders are working their socks off for the midfielders, the midfielders are working for the strikers… everybody wants to run and everybody has one target in their mind.
“We have to look at it game by game but everybody wants to be champions. I feel that I’m surrounded by champions. They know how to win and that makes it really easy for me.”
The free-scoring Dutchman, specially reserved praise for Mexican striker, Javier ‘Chicharito’ Hernandez, who also scored twice in the victory.
“[Javier and I] scored two goals each and he gave a really good pass for my first goal,” he added. “It was a good goal because every single touch was the right touch, in my opinion.
“The first one was a little behind me and I had to drag it onto my left foot. That was a good touch. Then I waited for the guy to slide in, had a good touch inside and then a quick finish. Three touches but all good touches.
“It was a very good performance we scored the goals at the right time. We’ve played Wigan twice this year and won 4-0 both times, so that’s good for goal difference.
“Everybody’s helping each other and everybody wants to share the goals. Look at the last goal – Danny wanted to give the ball to me so I could score. Everybody’s like that. I’m like that, Chicha is like that… everybody wants to share the goals and that, in my opinion, is the way to score heaps of goals.
“Hopefully we can keep it going. We’ve had a couple of games where we’ve had high scores but we want to score even more goals because that could be vital come the end of the season.”